I like interfaces that are flexible and use anchors, instead of being bound to a certain size.
Anchor's only go so far. Let's say you want your map element to be perfectly square. Someone is using a widescreen resolution, but it's anchored to be square on a regular resolution. If you hadn't compensated for the widescreen, your widescreen player will now have a lot of ugly and unprofessional blackspace.
Desktop is 1024x768 but anything around 640x480/800x600/fullscreen are all nice. If you were maybe referring to a built-in manner of detecting screen resolution you have my vote.